What kind of cancer causes high protein in the blood?
Multiple myeloma.
These cancer cells build up in the bone marrow and crowd out healthy cells. They also make M proteins. Higher levels of M protein in the blood can lead to complications.
A high total protein level could indicate dehydration or a certain type of cancer, such as multiple myeloma, that causes protein to accumulate abnormally. If the result of a total protein test is abnormal, further tests will be needed to identify which proteins are too high or too low.
Possible Causes
Chronic (long-term) inflammation or inflammatory disorders. Viral infections such as hepatitis B, hepatitis C or HIV/AIDS. Blood cancers such as multiple myeloma or certain types of lymphoma. Severe liver or kidney disease.
Tumor markers have traditionally been proteins or other substances that are made at higher amounts by cancer cells than normal cells. These can be found in the blood, urine, stool, tumors, or other tissues or bodily fluids of some patients with cancer.
In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.
High blood protein is an increase in the concentration of protein in the bloodstream. The medical term for high blood protein is hyperproteinemia. High blood protein is not a specific disease or condition, but it might indicate you have a disease. High blood protein rarely causes symptoms on its own.
High blood protein is not a specific disease or condition. It's usually a laboratory finding uncovered while evaluating another condition or symptom. For instance, high blood protein is found in people who are dehydrated. However, the real problem is that the blood plasma is actually more concentrated.
Can too much protein be harmful? The short answer is yes. As with most things in life, there can be too much of a good thing and if you eat too much protein, there may be a price to pay. For example, people that eat very high protein diets have a higher risk of kidney stones.
Drinking more water easily fixes the problem. You can prevent dehydration by making sure you always drink enough water. Adults need 1 quart of water (4 cups) for every 50 pounds of weight, or 2.5 quarts (10 cups) for a 125-pound person.
High levels of protein in your urine over a period of time may be the first sign that kidney disease or another condition has damaged the filters in your kidneys. A protein in urine test can help you find kidney damage early so you can make changes to protect your kidneys.
What blood results indicate cancer?
Higher-than-normal numbers of lymphocytes or monocytes can indicate the possibility of certain types of cancers. Some cancers and their treatments may cause neutropenia. Neutropenia is when a person has low numbers of neutrophils. This increases the chance of getting a bacterial infection.
Tumor marker tests use a sample of blood to look for chemicals made by cancer cells. These tests don't always help with diagnosing cancer because many healthy cells also make these chemicals. And some conditions that aren't cancer can cause high levels of tumor markers.

The Myc protein, depicted here, is mutated in more than half of all human cancers. A cancer-associated protein called Myc directly controls the expression of two molecules known to protect tumor cells from the host's immune system, according to a study by researchers at the Stanford University School of Medicine.
“Protein helps build and maintain muscle, which is important for cancer patients who might be having problems eating and are losing weight,” Schreiber says. “When they lose weight, it's often muscle and not fat, so protein is vital during treatment.”
HER2, a specialized protein that controls cancer growth and spread. It is found in some cancer cells. For example, breast and ovarian cancer cells. The RAS family of genes, which makes proteins involved in cell communication pathways, cell growth, and cell death.
Excess protein consumed is usually stored as fat, while the surplus of amino acids is excreted. This can lead to weight gain over time, especially if you consume too many calories while trying to increase your protein intake.
paraprotein in your blood that is more than 30 g/L. level of abnormal plasma cells in your bone marrow that is between 10% and 60%
Proteins with altered expression levels in cancer are involved in protein synthesis and degradation, signaling and metabolic pathways, DNA repair, apoptosis, and other cellular processes, whose alterations cause tumor development and progression.
High blood protein is an increase in the concentration of protein in the bloodstream. The medical term for high blood protein is hyperproteinemia. High blood protein is not a specific disease or condition, but it might indicate you have a disease. High blood protein rarely causes symptoms on its own.
High blood protein is not a specific disease or condition, but it might indicate you have a disease. High blood protein rarely causes symptoms on its own. But sometimes it is uncovered while you're having blood tests done for a separate issue or symptom.